Addressing Anemia and Quality of Life Through Current Evidence and Guideline-Based Practice in Lower-Risk Myelodysplastic Syndrome

Podcast 1: Diagnosis and Evaluation
Post-Test/Evaluation

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While low-risk MDS is diagnosed based on bone marrow biopsy results (blasts, cytogenetics, molecular studies) as well as labs, on initial patient presentation, which of the following complaints would be most consistent with early low-risk MDS?

Hemoglobin <10 g/dL and increased bruising/bleeding

Hepatomegaly or splenomegaly

Lymphadenopathy

Weight loss

A 66-year-old woman has dyslipidemia, hypertension, and COPD. She was treated for breast cancer 2 years ago with chemotherapy, and is currently in remission. She presents with anemia, and with low red and white cell counts, low platelets, and low hemoglobin levels. Which element of this patient’s history/presentation would be a warning sign for diagnosis of MDS?

Dyslipidemia

COPD

Hypertension

Recent history of chemotherapy