The Vision RELIEF Initiative: Transforming Care Through Next Generation Therapies in nAMD to Lower Burden and Improve Outcomes
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Ana is a 69-year-old Hispanic woman with neovascular age related macular degeneration (nAMD) who has recently moved from Venezuela. She requires treatment with anti-VEGF therapy, but she is often on-call for her part-time job, or caring for her young nephew, making it challenging for her to get to the retina specialist frequently. Which of the following statements about barriers to care is NOT true? 
Real-world studies have demonstrated significantly decreased durability of first-generation anti-VEGF therapy for the treatment of nAMD as compared to clinical trials. What impact does this more limited durability have on patients? 
After 6 months of treatment with aflibercept 8 mg Q10W, Stephania, a 56-year-old woman with nAMD of the right eye is visiting her specialist to assess her treatment plan. Her visual acuity is 20/25, with an absence of subretinal fluid. During the discussion, Stephania mentions that it’s becoming more challenging to get to the clinic. What would you do next? 
First-generation anti-VEGF agents, such as aflibercept 2 mg, repackaged bevacizumab, and ranibizumab, offer a variety of treatment options for nAMD. Which of the following statements about first-generation-therapies is FALSE
Donald is an 88-year-old man with nAMD in the left eye. He has decided to seek out a different retina specialist, due to the previous provider’s perception that anti-VEGF therapy will not benefit him because of his age and poor BCVA. While Donald is challenged with finding consistent transportation to his new clinic, he is motivated as he is actively writing the Great American Novel. Weighing durability and treatment burden, which of the following therapies would be most likely to be considered? 
Which of the following barriers to adherence is most likely to be addressed by next-generation anti-VEGF therapy in the treatment of nAMD? 
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