Examining Unmet Needs for Patients with Vasomotor Symptoms Due to MENOPAUSE: Challenges with Traditional Therapeutic Options and the Rationale for Novel Treatments
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Judy is a 48-year-old woman who has been struggling with vasomotor symptoms, specifically hot flashes and night sweats, for the past 2 years. Her symptoms are likely caused by dysregulation of the thermoregulatory zone by which type of KNDy neuron receptors?
KDR
GnRH
Neurokinin
PRA
Which of the following is an FDA-approved nonhormonal drug treatment option for women with vasomotor symptoms (VMS) due to menopause?
Paroxetine
Acupuncture
Progesterone
Propranolol
Linda is a 51-year-old woman with VMS. As she has a history of venous thrombosis, she is not a viable candidate for oral hormonal therapy. She has also suffered from refractory insomnia unrelated to menopause. As a part of shared decision making, her gynecologist included discussion of clinical trials testing neurokinin receptor agonists in women with VMS due to menopause. Which of the following approaches could potentially address both VMS and insomnia?
Fezolinetant
Elinzanetant
Paroxetine
All of the above
None of the above
Which of the following is recognized as an effective strategy for effective communication with patients who are considering treatment options for VMS?
Invite additional healthcare providers to advise in decision making about what the patient should take
Build a trusting relationship with the patient
Ensure the patient is the sole decision maker for treatment without provider input
Provide literature that supports only the most commonly suggested treatment strategy
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